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光线追踪法测算角膜屈光术后人工晶状体度数准确性评估

于周兴  李绍伟  霍冬梅  徐漫  石帅  刘畅  赵瑞华   

  1. 100021  北京爱尔英智眼科医院
  • 收稿日期:2018-08-22 出版日期:2019-03-25 发布日期:2019-03-28
  • 通讯作者: 李绍伟,Email:shaoweili2005@vip.163.com
  • 基金资助:

    爱尔眼科医院集团基金项目(AF152D01)

Evaluation of the accuracy of Sirius ray-tracing method for IOL power calculation in post-corneal-refractive-surgery eyes

YU Zhou-xing, LI Shao-wei, HUO Dong-mei, XU Man, SHI Shuai, LIU Chang, ZHAO Rui-hua   

  1. Beijing Aier-Intech Eye Hospital, Beijing 100021,China
  • Received:2018-08-22 Online:2019-03-25 Published:2019-03-28
  • Contact: LI Shao-wei, Email: shaoweili2005@vip.163.com

摘要:

目的  评估Sirius光线追踪法测算角膜屈光术后人工晶状体(IOL)度数的准确性。设计 比较性病例系列。研究对象  2015年6月至2017年12月在北京爱尔英智眼科医院行白内障超声乳化吸除联合IOL植入术的近视眼角膜屈光手术后白内障患者20例(23眼),其中LASIK术后21眼,PRK术后2眼。方法  在白内障术前用IOL Master测量眼轴长度、角膜曲率和前房深度,三维角膜地形图Sirius测量角膜屈光力、前房深度、房角宽度等眼前节数据;用Haigis-L公式、Barrett True K No History公式和Sirius光线追踪法分别计算出使白内障术后屈光度为零的IOL度数;取三种公式结果的平均值作为平均值法的结果。以Haigis-L公式为基础结合Barrett True K No History公式和Siruis光线追踪法的结果进行适当调整来选择实际植入的IOL度数。由同一术者完成白内障超声乳化吸除联合后房型IOL植入术。术后1个月采用主觉验光确定术后实际屈光度。计算四种方法的预测误差(术后实际的屈光不正度数和公式预测的屈光不正度数的差值)、绝对预测误差(预测误差的绝对值)、绝对预测误差分布(绝对预测误差在0.50 D内的百分比和绝对预测误差在1.0 D以内的百分比)。比较四种方法的绝对预测误差、绝对预测误差分布。主要指标  预测误差、绝对预测误差、绝对预测误差分布。结果  Sirius光线追踪法、Haigis-L公式、Barrett True K No History公式以及平均值法的预测误差分别为(+0.22±0.57)D、(-0.07±0.73)D、(-0.18±0.81)D、(-0.00±0.57)D,绝对预测误差分别为(0.47±0.38)D、(0.57±0.44)D、(0.64±0.52)D、(0.44±0.34)D。平均值法的绝对预测误差的平均值最小,但各种方法的绝对预测误差之间比较差异无统计学意义(P=0.364)。四种方法绝对预测误差≤0.50 D的分别为16眼(69.57%)、11眼(47.83%)、12眼(52.17%)、14眼(60.87%),差异无统计学意义(P=0.453);绝对预测误差≤1.0 D的分别为21眼(91.30%)、20眼(86.96%)、18眼(78.26%)、20眼(86.96%),差异无统计学意义(P=0.636)。结论  Sirius光线追踪法计算近视眼LASIK或PRK术后IOL度数时,比临床上常用且较准确的Haigis-L公式和Barrett True K No History公式预测误差的变异范围更小;Sirius光线追踪法有轻度的远视漂移;平均值法可用于人工晶状体度数的选择。(眼科, 2019, 28: 98-103)

关键词: 光线追踪, Haigis-L公式, Barrett True K No History公式, 人工晶状体, 准分子激光, Sirius 

Abstract:

Objective  To assess the accuracy of Sirius ray-tracing method for intraocular lens power calculation in post-corneal -refractive-surgery eyes. Design Comparative case series. Participants 21 post-LASIK eyes and 2 post-PRK eyes undergone phacoemulsification in Beijing Aier eye Hospital from June 2015 to December 2017. Methods The axial length, keratometry and anterior chamber depth was measured with IOL Master. The data of anterior segment including corneal power, anterior chamber depth and the angle of anterior chamber was measured with the Sirius three-dimensional corneal topography. The intraocular lens power was calculated using Sirius ray-tracing method, Haigis-L formula and Barrett True K No History formula. The implanting IOL power was determined mainly according to the result of Haigis-L formula, also referring to Barrett True K No History formula and Sirius ray-tracing method. All phacoemulsification operation were performed by the same operator. Postoperative refractions were measured with subjective refraction one month postoperatively. The predictive error (the difference between the actual postoperative refractive error and that predicted by the formula), the absolutely predictive error (the absolute value of the prediction error)and the absolutely predictive error distribution(the percentage of absolute prediction error within 0.50 D  and the percentage of absolute prediction error within 1.0 D) of the four methods were calculated. The absolutely predictive error and the absolutely predictive error distribution of different methods were compared. Main Outcome Measures The predictive error, the absolutely predictive error and the absolutely predictive error distribution of the four methods. Results The predictive error of the four methods was (+0.22±0.57)D, (-0.07±0.73) D, (-0.18±0.81) D, (-0.00±0.57) D respectively. The absolutely predictive error was (0.47±0.38)D, (0.57±0.44) D, (0.64±0.52) D, (0.44±0.34) D respectively. The absolutely predictive error of the mean value method was the lowest, but there was no statistical difference in all the formulas (P=0.364). The absolutely predictive error of Sirius ray-tracing method was no more than 0.5 D in 16 eyes (69.57%), and no more than 1.0 D in 18 eyes (91.30%). The absolutely predictive error of Haigis-L formula was no more than 0.5 D in 11 eyes (47.83%), and no more than 1.0 D in 20 eyes (86.96%). The absolutely predictive error of Barrett True K No History formula was no more than 0.5 D in 12 eyes (52.17%), and no more than 1.0 D in 18 eyes (78.26%). The absolutely predictive error of the mean value method was no more than 0.5 D in 14 eyes (60.87%), and no more than 1.0 D in 20 eyes (86.96%). There was no statistical difference in all the formulas in the number of eyes in which the absolutely predictive error was no more than 0.50 D (P=0.453), and there was also no statistical difference in the number of eyes no more than 1.0 D (P=0.636). Conclusions  When used in IOL power calculation in post-LASIK or post-PRK eyes, the range of variation of Sirius ray-tracing method was narrower than Haigis-L formula and Barrett True K No History formula  which were commonly used in clinically. Sirius ray-tracing method could result mild hyperopia. The mean value method should be used in the IOL power for post-corneal-refractive-surgery eyes. (Ophthalmol CHN, 2019, 28: 98-103)

Key words: ray-tracing, Haigis-L formula, Barrett True K No history formula, intraocular lens, excimer laser, Sirius